Spiral microfluidic biosensor for exosome detection

Project description

Our research team has recently developed and brought to commercial translation a new technology for bladder cancer screening. In collaboration with Flinders Medical Centre, this project aims to translate this biotechnology to prostate cancer diagnostic, via the specific capture of exosomes. The proposed device consists of a spiral microfluidic chip and an electrochemical sensor coated with a functional plasma polymer. The design of the spiral will be optimised to selectively isolate nano-sized particles (i.e. exosomes) from larger ones (i.e. cells). The thickness and reactivity of the plasma polymer will be optimized to increase the sensitivity of the electrochemical biosensor. This research is performed in collaboration with Flinders Medical centre and is supported by the Australian Research Council.

Co-supervisors

Prof Jonathan Gleadle

Further information

About the supervisor: I will be joining Flinders University as a member of the College of Science and Engineering and the Institute for Nanoscale Science & Technology in November 2021. My research is intrinsically cross-disciplinary, using surface science and chemistry to develop new nanotechnology for the biomedical and energy fields.

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You must also contact each supervisor directly to discuss both the project details and your suitability to undertake the project.